ZFIN is now using GRCz12tu for Genomic Data
Gene
lsm7
- ID
- ZDB-GENE-030131-8284
- Name
- LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated
- Symbol
- lsm7 Nomenclature History
- Previous Names
-
- fj64g01
- wu:fj64g01
- zgc:66405
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to contribute to RNA binding activity. Acts upstream of or within regulation of oligodendrocyte apoptotic process; response to light stimulus; and swimming behavior. Predicted to be located in nucleus. Predicted to be part of Lsm1-7-Pat1 complex; spliceosomal complex; and spliceosomal snRNP complex. Is expressed in nervous system. Human ortholog(s) of this gene implicated in leukodystrophy. Orthologous to human LSM7 (LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7136286 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Derksen et al., 2021
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| leukodystrophy and cerebellar atrophy | Alliance | Leukodystrophy and cerebellar atrophy | 621191 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | LSM domain superfamily | Sm domain | Sm domain, eukaryotic/archaea-type | Sm-like protein Lsm7 | Sm-like protein Lsm7/SmG |
|---|---|---|---|---|---|---|---|
| UniProtKB:Q7SXE2 | InterPro | 49 | |||||
| UniProtKB:A4FVI7 | InterPro | 103 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers