Gene
ttbk2b
- ID
- ZDB-GENE-030131-8246
- Name
- tau tubulin kinase 2b
- Symbol
- ttbk2b Nomenclature History
- Previous Names
-
- fj62e10
- sb:eu1102
- si:dkey-12h9.11
- si:dkey-12h9.14
- wu:fj62e10
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to have protein serine/threonine kinase activity. Predicted to be involved in cilium assembly and peptidyl-serine phosphorylation. Predicted to localize to several cellular components, including ciliary basal body; ciliary transition zone; and nucleus. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 11. Orthologous to human TTBK2 (tau tubulin kinase 2).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 1 figure from Thisse et al., 2005
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu1102 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
spinocerebellar ataxia type 11 | Alliance | Spinocerebellar ataxia 11 | 604432 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Binding_site | IPR017441 | Protein kinase, ATP binding site |
Domain | IPR000719 | Protein kinase domain |
Domain | IPR047916 | Tau-tubulin kinase homolog Asator-like, catalytic domain |
Family | IPR050235 | Casein Kinase 1 Ser/Thr Protein Kinase |
Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
Domain Details Per Protein
Protein | Length | Casein Kinase 1 Ser/Thr Protein Kinase | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Tau-tubulin kinase homolog Asator-like, catalytic domain |
---|---|---|---|---|---|---|
UniProtKB:F1RC23
|
928 |
Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
ttbk2b-201
(1)
|
Ensembl | 5,277 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance