Gene

ttbk2b

ID
ZDB-GENE-030131-8246
Name
tau tubulin kinase 2b
Symbol
ttbk2b Nomenclature History
Previous Names
  • fj62e10
  • sb:eu1102
  • si:dkey-12h9.11
  • si:dkey-12h9.14
  • wu:fj62e10
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Predicted to have protein serine/threonine kinase activity. Predicted to be involved in cilium assembly and peptidyl-serine phosphorylation. Predicted to localize to several cellular components, including ciliary basal body; ciliary transition zone; and nucleus. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 11. Orthologous to human TTBK2 (tau tubulin kinase 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2005
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ttbk2b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
spinocerebellar ataxia type 11 Alliance Spinocerebellar ataxia 11 604432
Associated With ttbk2b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000719 Protein kinase domain
Domain IPR047916 Tau-tubulin kinase homolog Asator-like, catalytic domain
Family IPR050235 Casein Kinase 1 Ser/Thr Protein Kinase
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Domain Details Per Protein
Protein Length Casein Kinase 1 Ser/Thr Protein Kinase Protein kinase, ATP binding site Protein kinase domain Protein kinase-like domain superfamily Tau-tubulin kinase homolog Asator-like, catalytic domain
UniProtKB:F1RC23 928
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA ttbk2b-201 (1) Ensembl 5,277 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations