ZFIN is now using GRCz12tu for Genomic Data
Gene
tomm70
- ID
- ZDB-GENE-030131-8173
- Name
- translocase of outer mitochondrial membrane 70
- Symbol
- tomm70 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to contribute to transmembrane protein transporter activity. Acts upstream of or within mitochondrion transport along microtubule; myelination; and ventricular cardiac muscle cell development. Predicted to be located in axon cytoplasm; dendrite cytoplasm; and mitochondrion. Predicted to be active in mitochondrial outer membrane. Is expressed in several structures, including alar plate midbrain region; digestive system; musculature system; nervous system; and optic vesicle. Used to study hereditary spastic paraplegia. Orthologous to human TOMM70 (translocase of outer mitochondrial membrane 70).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:73188 (9 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| hereditary spastic paraplegia | tomm70p25ca/p25ca | standard conditions | Garg et al., 2025 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Tetratricopeptide-like helical domain superfamily | Tetratricopeptide repeat |
|---|---|---|---|---|
| UniProtKB:Q6PBY6 | InterPro | 578 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
tomm70a-201
(1)
|
Ensembl | 1,981 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers