Gene
cnksr2b
- ID
- ZDB-GENE-030131-8048
- Name
- connector enhancer of kinase suppressor of Ras 2b
- Symbol
- cnksr2b Nomenclature History
- Previous Names
-
- fj48e09
- si:dkey-92k1.12
- wu:fj48e09 (1)
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to be involved in regulation of signal transduction. Predicted to localize to cytoplasm and membrane. Human ortholog(s) of this gene implicated in syndromic X-linked mental retardation Hough type. Orthologous to human CNKSR2 (connector enhancer of kinase suppressor of Ras 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| syndromic X-linked mental retardation Hough type | Alliance | Intellectual developmental disorder, X-linked syndromic, Houge type | 301008 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001478 | PDZ domain |
| Domain | IPR001660 | Sterile alpha motif domain |
| Domain | IPR001849 | Pleckstrin homology domain |
| Domain | IPR010599 | Connector enhancer of kinase suppressor of ras 2/3 domain |
| Domain | IPR017874 | CRIC domain |
| Domain | IPR049628 | CNK1-3, SAM domain |
| Family | IPR051566 | Connector enhancer of kinase suppressor of Ras |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR013761 | Sterile alpha motif/pointed domain superfamily |
| Homologous_superfamily | IPR036034 | PDZ superfamily |
Domain Details Per Protein
| Protein | Length | CNK1-3, SAM domain | Connector enhancer of kinase suppressor of Ras | Connector enhancer of kinase suppressor of ras 2/3 domain | CRIC domain | PDZ domain | PDZ superfamily | PH-like domain superfamily | Pleckstrin homology domain | Sterile alpha motif domain | Sterile alpha motif/pointed domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:E7FAZ0
|
963 | ||||||||||
|
UniProtKB:A0A8M3AM98
|
969 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cnksr2b-201
(1)
|
Ensembl | 3,352 nt | ||
| mRNA |
cnksr2b-203
(1)
|
Ensembl | 2,409 nt | ||
| mRNA |
cnksr2b-204
(1)
|
Ensembl | 7,988 nt | ||
| ncRNA |
cnksr2b-002
(1)
|
Ensembl | 494 nt |
Interactions and Pathways
No data available
Plasmids
No data available