Gene
ndst1b
- ID
- ZDB-GENE-030131-8022
- Name
- N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1b
- Symbol
- ndst1b Nomenclature History
- Previous Names
-
- ndst1
- fj47c03
- wu:fj47c03
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Exhibits [heparan sulfate]-glucosamine N-sulfotransferase activity. Involved in sulfation and vasculogenesis. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Is expressed in several structures, including hindbrain; intermediate cell mass of mesoderm; myotome; pectoral fin; and somite. Orthologous to human NDST1 (N-deacetylase and N-sulfotransferase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from Filipek-Górniok et al., 2015
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Harfouche et al., 2009
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal recessive intellectual developmental disorder 46 | Alliance | Intellectual developmental disorder, autosomal recessive 46 | 616116 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Heparan sulfate sulfotransferase | Heparan sulphate-N-deacetylase | P-loop containing nucleoside triphosphate hydrolase | Sulfotransferase domain |
|---|---|---|---|---|---|
|
UniProtKB:A0A0R4IR84
|
886 |
Interactions and Pathways
No data available
Plasmids
No data available