Gene

rcbtb1

ID

ZDB-GENE-030131-7951

Name

regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1

Symbol

rcbtb1 Nomenclature History

Previous Names

fj43a07
wu:fj43a07
zgc:56037 (1)

Type

protein_coding_gene

Location

Chr: 1 Mapping Details/Browsers

Description

Involved in blood vessel development and retina vasculature development in camera-type eye. Orthologous to human RCBTB1 (RCC1 and BTB domain containing protein 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:56037 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 3 figures from Wu et al., 2016
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With rcbtb1 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Retinal dystrophy with or without extraocular anomalies	617175

Associated With rcbtb1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000210	BTB/POZ domain
Domain	IPR047996	RCC1 and BTB domain-containing protein 1, BTB/POZ domain
Family	IPR051625	Diverse Signaling and Regulatory Domain-Containing Protein
Homologous_superfamily	IPR009091	Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II
Homologous_superfamily	IPR011333	SKP1/BTB/POZ domain superfamily
Repeat	IPR000408	Regulator of chromosome condensation, RCC1

Domain Details Per Protein

Protein	Length	BTB/POZ domain	Diverse Signaling and Regulatory Domain-Containing Protein	RCC1 and BTB domain-containing protein 1, BTB/POZ domain	Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II	Regulator of chromosome condensation, RCC1	SKP1/BTB/POZ domain superfamily
UniProtKB:Q7ZVG0 InterPro	531
UniProtKB:B8A4R1 InterPro	531

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	rcbtb1-201 (1) Ensembl	Ensembl	2,750 nt	Select Tool
mRNA	rcbtb1-202 (1) Ensembl	Ensembl	801 nt	Select Tool
mRNA	rcbtb1-203 (1) Ensembl	Ensembl	1,613 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations