Gene
irf2bp2a
- ID
- ZDB-GENE-030131-7809
- Name
- interferon regulatory factor 2 binding protein 2a
- Symbol
- irf2bp2a Nomenclature History
- Previous Names
-
- fj35c12
- wu:fj35c12
- zgc:56251
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to have transcription corepressor activity and ubiquitin protein ligase activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in common variable immunodeficiency. Is expressed in several structures, including midbrain neural keel; musculature system; nervous system; periderm; and presumptive diencephalon. Orthologous to human IRF2BP2 (interferon regulatory factor 2 binding protein 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:56251 (10 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| common variable immunodeficiency 14 | Alliance | ?Immunodeficiency, common variable, 14 | 617765 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Interferon regulatory factor 2-binding protein 1/2, C3HC4-type RING finger superfamily | Interferon regulatory factor 2-binding protein 1 & 2, zinc finger |
|---|---|---|---|
|
UniProtKB:Q6NZT6
|
491 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
irf2bp2a-201
(1)
|
Ensembl | 1,001 nt |
Interactions and Pathways
No data available
Plasmids
No data available