ZFIN is now using GRCz12tu for Genomic Data
Gene
gas6
- ID
- ZDB-GENE-030131-7773
- Name
- growth arrest-specific 6
- Symbol
- gas6 Nomenclature History
- Previous Names
-
- fj34a12
- wu:fj34a12
- zgc:63860
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable calcium ion binding activity. Acts upstream of or within sprouting angiogenesis. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in heart; nervous system; and neural tube. Human ortholog(s) of this gene implicated in stroke. Orthologous to human GAS6 (growth arrest specific 6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 15 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:63860 (9 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018097 | EGF-like calcium-binding, conserved site |
| Domain | IPR000294 | Gamma-carboxyglutamic acid-rich (GLA) domain |
| Domain | IPR000742 | EGF-like domain |
| Domain | IPR001791 | Laminin G domain |
| Domain | IPR001881 | EGF-like calcium-binding domain |
| Domain | IPR049883 | NOTCH1 EGF-like calcium-binding domain |
| Family | IPR051145 | Growth Arrest-Specific/Sex Hormone-Binding/Vitamin K-Dependent |
| Homologous_superfamily | IPR013320 | Concanavalin A-like lectin/glucanase domain superfamily |
| Homologous_superfamily | IPR017857 | Coagulation factor-like, Gla domain superfamily |
| Homologous_superfamily | IPR035972 | Gamma-carboxyglutamic acid-rich (GLA) domain superfamily |
| PTM | IPR000152 | EGF-type aspartate/asparagine hydroxylation site |
Domain Details Per Protein
| Protein | Additional Resources | Length | Coagulation factor-like, Gla domain superfamily | Concanavalin A-like lectin/glucanase domain superfamily | EGF-like calcium-binding, conserved site | EGF-like calcium-binding domain | EGF-like domain | EGF-type aspartate/asparagine hydroxylation site | Gamma-carboxyglutamic acid-rich (GLA) domain | Gamma-carboxyglutamic acid-rich (GLA) domain superfamily | Growth Arrest-Specific/Sex Hormone-Binding/Vitamin K-Dependent | Laminin G domain | NOTCH1 EGF-like calcium-binding domain |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q7T3H4 | InterPro | 648 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers