Gene
cox6a1
- ID
- ZDB-GENE-030131-7715
- Name
- cytochrome c oxidase subunit 6A1
- Symbol
- cox6a1 Nomenclature History
- Previous Names
-
- ns:zf-e250
- zgc:103782
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to enable enzyme regulator activity. Predicted to be involved in mitochondrial electron transport, cytochrome c to oxygen. Predicted to be located in mitochondrial inner membrane. Predicted to be part of respiratory chain complex IV. Is expressed in several structures, including alar plate midbrain region; brain; eye; liver; and muscle. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease recessive intermediate D and mitochondrial complex IV deficiency nuclear type 18. Orthologous to several human genes including COX6A1 (cytochrome c oxidase subunit 6A1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6896829 (8 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Charcot-Marie-Tooth disease recessive intermediate D | Alliance | Charcot-Marie-Tooth disease, recessive intermediate D | 616039 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Cytochrome c oxidase, subunit VIa | Cytochrome c oxidase, subunit VIa, conserved site | Cytochrome c oxidase, subunit VIa superfamily |
|---|---|---|---|---|---|
| UniProtKB:Q642I9 | InterPro | 108 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cox6a1-201
(1)
|
Ensembl | 627 nt | ||
| ncRNA |
cox6a1-002
(1)
|
Ensembl | 703 nt |
Interactions and Pathways
No data available
Plasmids
No data available