Gene

cox6a1

ID
ZDB-GENE-030131-7715
Name
cytochrome c oxidase subunit 6A1
Symbol
cox6a1 Nomenclature History
Previous Names
  • ns:zf-e250
  • zgc:103782
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Predicted to enable enzyme regulator activity. Predicted to be involved in mitochondrial electron transport, cytochrome c to oxygen. Predicted to be located in mitochondrial inner membrane. Predicted to be part of respiratory chain complex IV. Is expressed in several structures, including alar plate midbrain region; brain; eye; liver; and muscle. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease recessive intermediate D and mitochondrial complex IV deficiency nuclear type 18. Orthologous to several human genes including COX6A1 (cytochrome c oxidase subunit 6A1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cox6a1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Charcot-Marie-Tooth disease recessive intermediate D Alliance Charcot-Marie-Tooth disease, recessive intermediate D 616039
1 - 1 of 1
Associated With cox6a1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018507 Cytochrome c oxidase, subunit VIa, conserved site
Family IPR001349 Cytochrome c oxidase, subunit VIa
Homologous_superfamily IPR036418 Cytochrome c oxidase, subunit VIa superfamily
1 - 3 of 3
Domain Details Per Protein
Protein Additional Resources Length Cytochrome c oxidase, subunit VIa Cytochrome c oxidase, subunit VIa, conserved site Cytochrome c oxidase, subunit VIa superfamily
UniProtKB:Q642I9 InterPro 108
1 - 1 of 1
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA cox6a1-201 (1)
Ensembl
Ensembl 627 nt
ZFIN BLAST
ncRNA cox6a1-002 (1)
Ensembl
Ensembl 703 nt
ZFIN BLAST
1 - 2 of 2
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations
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