Gene

elovl4b

ID
ZDB-GENE-030131-7672
Name
ELOVL fatty acid elongase 4b
Symbol
elovl4b Nomenclature History
Previous Names
  • elovl4
  • wu:fk62b04
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Description
Predicted to have fatty acid elongase activity. Involved in very long-chain fatty acid biosynthetic process. Predicted to localize to integral component of endoplasmic reticulum membrane. Is expressed in optic vesicle; pleuroperitoneal region; presumptive neural retina; solid lens vesicle; and visual system. Human ortholog(s) of this gene implicated in corneal dystrophy and spinocerebellar ataxia type 34. Orthologous to human ELOVL4 (ELOVL fatty acid elongase 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
11 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With elovl4b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
spinocerebellar ataxia type 34 Alliance Spinocerebellar ataxia 34 133190
Stargardt disease Alliance Stargardt disease 3 600110
Ichthyosis, spastic quadriplegia, and mental retardation 614457
Associated With elovl4b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR030457 ELO family, conserved site
Family IPR002076 ELO family
Family IPR033678 Elongation of very long chain fatty acids protein 4
Domain Details Per Protein
Protein Length ELO family ELO family, conserved site Elongation of very long chain fatty acids protein 4
UniProtKB:Q6P978 303
UniProtKB:A7MCJ3 300
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations