Gene
unc119c
- ID
- ZDB-GENE-030131-7635
- Name
- unc-119 lipid binding chaperone c
- Symbol
- unc119c Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to have lipid binding activity. Involved in optomotor response and regulation of axon extension involved in axon guidance. Predicted to localize to intercellular bridge and microtubule cytoskeleton. Used to study cone-rod dystrophy. Human ortholog(s) of this gene implicated in idiopathic CD4-positive T-lymphocytopenia. Is expressed in epiphysis and retina. Orthologous to human UNC119 (unc-119 lipid binding chaperone).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| cone-rod dystrophy | WT + MO3-unc119c | standard conditions | Rainy et al., 2016 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | GMP phosphodiesterase, delta subunit | GMP phosphodiesterase, delta subunit superfamily | Immunoglobulin E-set | PDE6D/unc-119 myristoyl-binding |
|---|---|---|---|---|---|
|
UniProtKB:E7F2M1
|
261 | ||||
|
UniProtKB:A0A8M3AR02
|
261 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
unc119.2-201
(1)
|
Ensembl | 786 nt | ||
| mRNA |
unc119.2-202
(1)
|
Ensembl | 1,161 nt |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-unc119.2 | polyclonal | Rabbit |
|
1 |
Plasmids
No data available