ZFIN is now using GRCz12tu for Genomic Data
Gene
unc119c
- ID
- ZDB-GENE-030131-7635
- Name
- unc-119 lipid binding chaperone c
- Symbol
- unc119c Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable lipid binding activity. Acts upstream of or within optomotor response and regulation of axon extension involved in axon guidance. Predicted to be active in intercellular bridge and microtubule cytoskeleton. Is expressed in epiphysis; eye photoreceptor cell; olfactory pit; otic vesicle; and retina. Used to study cone-rod dystrophy.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| cone-rod dystrophy | WT + MO3-unc119c | standard conditions | Rainy et al., 2016 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | GMP phosphodiesterase, delta subunit | GMP phosphodiesterase, delta subunit superfamily | Immunoglobulin E-set | PDE6D/unc-119 myristoyl-binding |
|---|---|---|---|---|---|---|
| UniProtKB:E7F2M1 | InterPro | 261 | ||||
| UniProtKB:A0A8M3AR02 | InterPro | 261 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
unc119.2-201
(1)
|
Ensembl | 786 nt | ||
| mRNA |
unc119.2-202
(1)
|
Ensembl | 1,161 nt |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-unc119.2 | polyclonal | Rabbit |
|
1 |
Plasmids
No data available
- Genome Browsers