ZFIN is now using GRCz12tu for Genomic Data
Gene
kat8
- ID
- ZDB-GENE-030131-7510
- Name
- K(lysine) acetyltransferase 8
- Symbol
- kat8 Nomenclature History
- Previous Names
-
- myst1
- wu:fb22g02
- wu:fj22d09
- zgc:66387
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable histone H4K16 acetyltransferase activity. Acts upstream of or within primitive hemopoiesis. Predicted to be located in nucleus. Predicted to be part of MSL complex; NSL complex; and NuA4 histone acetyltransferase complex. Orthologous to human KAT8 (lysine acetyltransferase 8).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7153119 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Huang et al., 2013
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Li-Ghorgani-Weisz-Hubshman syndrome | 618974 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000953 | Chromo/chromo shadow domain |
| Domain | IPR002717 | Histone acetyltransferase domain, MYST-type |
| Domain | IPR025995 | RNA binding activity-knot of a chromodomain |
| Domain | IPR040706 | MYST, zinc finger domain |
| Family | IPR050603 | MYST family histone acetyltransferases |
| Homologous_superfamily | IPR016181 | Acyl-CoA N-acyltransferase |
| Homologous_superfamily | IPR016197 | Chromo-like domain superfamily |
| Homologous_superfamily | IPR036388 | Winged helix-like DNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Acyl-CoA N-acyltransferase | Chromo/chromo shadow domain | Chromo-like domain superfamily | Histone acetyltransferase domain, MYST-type | MYST family histone acetyltransferases | MYST, zinc finger domain | RNA binding activity-knot of a chromodomain | Winged helix-like DNA-binding domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q7SXF3 | InterPro | 487 | ||||||||
| UniProtKB:A0A8M1PHR3 | InterPro | 487 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers