Gene
ppiab
- ID
- ZDB-GENE-030131-7459
- Name
- peptidylprolyl isomerase Ab (cyclophilin A)
- Symbol
- ppiab Nomenclature History
- Previous Names
-
- ppial
- cyclophilin (1)
- wu:fj18g05
- zgc:73102
- zgc:86688
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to enable cyclosporin A binding activity and peptidyl-prolyl cis-trans isomerase activity. Acts upstream of or within response to hypoxia. Predicted to be located in extracellular region and nucleus. Predicted to be active in cytoplasm. Is expressed in brain. Human ortholog(s) of this gene implicated in cholangiocarcinoma and human immunodeficiency virus infectious disease. Orthologous to human PPIA (peptidylprolyl isomerase A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:73102 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR020892 | Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site |
| Domain | IPR002130 | Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain |
| Family | IPR024936 | Cyclophilin-type peptidyl-prolyl cis-trans isomerase |
| Homologous_superfamily | IPR029000 | Cyclophilin-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Cyclophilin-like domain superfamily | Cyclophilin-type peptidyl-prolyl cis-trans isomerase | Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site | Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain |
|---|---|---|---|---|---|
|
UniProtKB:Q6PC53
|
164 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available