Gene

arpc1b

ID
ZDB-GENE-030131-7414
Name
actin related protein 2/3 complex, subunit 1B
Symbol
arpc1b Nomenclature History
Previous Names
  • cb871 (1)
  • fj15h02
  • wu:fj08e12
  • wu:fj15h02
  • zgc:64056
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to have actin filament binding activity. Involved in T cell differentiation and thrombocyte differentiation. Predicted to localize to Arp2/3 protein complex. Human ortholog(s) of this gene implicated in gastritis and myelodysplastic syndrome. Is expressed in blood; blood island; pectoral fin musculature; pharyngeal arch 3-7 skeleton; and ventral wall of dorsal aorta. Orthologous to human ARPC1B (actin related protein 2/3 complex subunit 1B).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
5 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Somech et al., 2017
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With arpc1b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
immunodeficiency 71 Alliance Immunodeficiency 71 with inflammatory disease and congenital thrombocytopenia 617718
Associated With arpc1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR017383 Actin-related protein 2/3 complex subunit 1
Family IPR030141 Actin-related protein 2/3 complex subunit 1B
Homologous_superfamily IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily IPR036322 WD40-repeat-containing domain superfamily
Repeat IPR001680 WD40 repeat
Domain Details Per Protein
Protein Length Actin-related protein 2/3 complex subunit 1 Actin-related protein 2/3 complex subunit 1B WD40 repeat WD40-repeat-containing domain superfamily WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:Q7T372 369
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations