Gene

srsf5a

ID

ZDB-GENE-030131-7336

Name

serine and arginine rich splicing factor 5a

Symbol

srsf5a Nomenclature History

Previous Names

sfrs5
sfrs5a
fb49e01
im:6906390
wu:fb49e01
wu:fj09b12

Type

protein_coding_gene

Location

Chr: 13 Mapping Details/Browsers

Description

Predicted to enable mRNA binding activity. Predicted to act upstream of or within RNA splicing and mRNA processing. Predicted to be part of ribonucleoprotein complex. Predicted to be active in cytoplasm and nucleus. Is expressed in nervous system; otic vesicle; pectoral fin; pharyngeal arch; and solid lens vesicle. Orthologous to human SRSF5 (serine and arginine rich splicing factor 5).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

4 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:6906390 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 2 figures from Joris et al., 2017
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With srsf5a Human Ortholog

No data available

Associated With srsf5a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000504	RNA recognition motif domain
Domain	IPR047190	Serine/arginine-rich splicing factor 4 (SRSF4)-like, RNA recognition motif 2
Family	IPR050374	RRT5/SRSF/Splicing Factor SR
Homologous_superfamily	IPR012677	Nucleotide-binding alpha-beta plait domain superfamily
Homologous_superfamily	IPR035979	RNA-binding domain superfamily

Domain Details Per Protein

Protein	Length	Nucleotide-binding alpha-beta plait domain superfamily	RNA-binding domain superfamily	RNA recognition motif domain	RRT5/SRSF/Splicing Factor SR	Serine/arginine-rich splicing factor 4 (SRSF4)-like, RNA recognition motif 2
UniProtKB:Q6TGT9 InterPro	259
UniProtKB:F8W2Y8 InterPro	133

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
aberrant processed transcript	srsf5a-203 (1) Ensembl	Ensembl	1,514 nt	Select Tool ZFIN BLAST
mRNA	srsf5a-201 (1) Ensembl	Ensembl	1,310 nt	Select Tool ZFIN BLAST
mRNA	srsf5a-205 (1) Ensembl	Ensembl	4,629 nt	Select Tool ZFIN BLAST
mRNA	srsf5a-206 (1) Ensembl	Ensembl	4,722 nt	Select Tool ZFIN BLAST
mRNA	srsf5a-207 (1) Ensembl	Ensembl	427 nt	Select Tool ZFIN BLAST
ncRNA	srsf5a-002 (1) Ensembl	Ensembl	2,356 nt	Select Tool ZFIN BLAST
ncRNA	srsf5a-004 (1) Ensembl	Ensembl	715 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations