ZFIN is now using GRCz12tu for Genomic Data
Gene
mak
- ID
- ZDB-GENE-030131-7279
- Name
- male germ cell-associated kinase
- Symbol
- mak Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable protein serine/threonine kinase activity. Acts upstream of or within motile cilium assembly. Predicted to be located in cytoskeleton. Predicted to be active in cilium; cytoplasm; and nucleus. Is expressed in several structures, including Kupffer's vesicle; brain; forerunner cell group; optic cup; and visual system. Human ortholog(s) of this gene implicated in retinitis pigmentosa 62. Orthologous to human MAK (male germ cell associated kinase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:56603 (9 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| retinitis pigmentosa 62 | Alliance | Retinitis pigmentosa 62 | 614181 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site |
|---|---|---|---|---|---|---|
| UniProtKB:F1QUT2 | InterPro | 633 | ||||
| UniProtKB:A0A8M9PFV2 | InterPro | 590 | ||||
| UniProtKB:A0A8M3ANF8 | InterPro | 600 | ||||
| UniProtKB:A0A8M2B9R2 | InterPro | 601 | ||||
| UniProtKB:Q7ZTX0 | InterPro | 633 | ||||
| UniProtKB:A0A286Y937 | InterPro | 632 | ||||
| UniProtKB:A0AC58IPH9 | InterPro | 590 | ||||
| UniProtKB:A0AC58IPI0 | InterPro | 601 | ||||
| UniProtKB:A0AC58IPI1 | InterPro | 600 | ||||
| UniProtKB:A0AC58IPI2 | InterPro | 633 | ||||
| UniProtKB:A0AC58IPI3 | InterPro | 601 | ||||
| UniProtKB:A0AC58IPI9 | InterPro | 558 | ||||
| UniProtKB:A0AC58IPJ0 | InterPro | 558 | ||||
| UniProtKB:A0AC58IPJ2 | InterPro | 537 | ||||
| UniProtKB:A0AC58IPJ3 | InterPro | 537 | ||||
| UniProtKB:A0AC58IPJ4 | InterPro | 462 | ||||
| UniProtKB:A0AC58IPJ5 | InterPro | 494 | ||||
| UniProtKB:A0AC58IPJ7 | InterPro | 589 | ||||
| UniProtKB:A0AC58IPJ8 | InterPro | 505 | ||||
| UniProtKB:A0AC58IPJ9 | InterPro | 589 | ||||
| UniProtKB:A0AC58IPK2 | InterPro | 494 | ||||
| UniProtKB:A0AC58IPK4 | InterPro | 505 | ||||
| UniProtKB:A0AC58IPL1 | InterPro | 557 | ||||
| UniProtKB:A0AC58IPL4 | InterPro | 557 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
- Genome Browsers