Gene

hcls1

ID
ZDB-GENE-030131-7191
Name
hematopoietic cell-specific Lyn substrate 1
Symbol
hcls1 Nomenclature History
Previous Names
  • fk96b08
  • si:dkey-9a20.6
  • wu:fk96b08
  • zgc:154014
Type
protein_coding_gene
Location
Chr: 4 Mapping Details/Browsers
Description
Predicted to have actin filament binding activity. Predicted to be involved in generation of neurons; postsynaptic actin cytoskeleton organization; and regulation of actin filament polymerization. Predicted to colocalize with actin filament. Orthologous to human HCLS1 (hematopoietic cell-specific Lyn substrate 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With hcls1 Human Ortholog
No data available
Associated With hcls1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001452 SH3 domain
Homologous_superfamily IPR036028 SH3-like domain superfamily
Repeat IPR003134 Hs1/Cortactin
Domain Details Per Protein
Protein Length Hs1/Cortactin SH3 domain SH3-like domain superfamily
UniProtKB:Q1LWS2 548
UniProtKB:A0A8M2BC47 513
UniProtKB:A0A0R4I9Q9 550
UniProtKB:A0A8M2BC39 476
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA hcls1-201 (1) Ensembl 2,495 nt
mRNA hcls1-202 (1) Ensembl 1,655 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations