Gene
hcls1
- ID
- ZDB-GENE-030131-7191
- Name
- hematopoietic cell-specific Lyn substrate 1
- Symbol
- hcls1 Nomenclature History
- Previous Names
-
- fk96b08
- si:dkey-9a20.6
- wu:fk96b08
- zgc:154014
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to enable actin filament binding activity. Predicted to be involved in cell migration and regulation of actin filament polymerization. Predicted to be active in cortical actin cytoskeleton; plasma membrane; and site of polarized growth. Predicted to colocalize with actin filament. Orthologous to human HCLS1 (hematopoietic cell-specific Lyn substrate 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Hs1/Cortactin | SH3 domain | SH3-like domain superfamily |
|---|---|---|---|---|---|
| UniProtKB:Q1LWS2 | InterPro | 548 | |||
| UniProtKB:A0A8M2BC47 | InterPro | 513 | |||
| UniProtKB:A0A0R4I9Q9 | InterPro | 550 | |||
| UniProtKB:A0A8M2BC39 | InterPro | 476 |
Interactions and Pathways
No data available
Plasmids
No data available