Gene
chd1
- ID
- ZDB-GENE-030131-7120
- Name
- chromodomain helicase DNA binding protein 1
- Symbol
- chd1 Nomenclature History
- Previous Names
-
- fc26h11
- fk85d05
- si:dkey-106m21.4
- wu:fc26h11
- wu:fk85d05 (1)
- zgc:173506
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to enable several functions, including ATP hydrolysis activity; ATP-dependent chromatin remodeler activity; and histone binding activity. Predicted to be involved in nucleosome organization and regulation of transcription by RNA polymerase II. Predicted to be active in chromatin and nucleus. Human ortholog(s) of this gene implicated in castration-resistant prostate carcinoma and prostate cancer. Orthologous to human CHD1 (chromodomain helicase DNA binding protein 1).
- Genome Resources
- Note
-
corresponds to ENSDARG00000014878, Chr10
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Pilarowski-Bjornsson syndrome | 617682 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR023779 | Chromo domain, conserved site |
| Domain | IPR000330 | SNF2, N-terminal |
| Domain | IPR000953 | Chromo/chromo shadow domain |
| Domain | IPR001650 | Helicase, C-terminal domain-like |
| Domain | IPR014001 | Helicase superfamily 1/2, ATP-binding domain |
| Domain | IPR023780 | Chromo domain |
| Domain | IPR025260 | Chromodomain-helicase-DNA-binding protein 1-like, C-terminal domain |
| Domain | IPR040793 | CDH1/2, SANT-Helical linker 1 |
| Domain | IPR049730 | SNF2/RAD5-like, C-terminal helicase domain |
| Homologous_superfamily | IPR016197 | Chromo-like domain superfamily |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR038718 | SNF2-like, N-terminal domain superfamily |
Domain Details Per Protein
| Protein | Length | CDH1/2, SANT-Helical linker 1 | Chromo/chromo shadow domain | Chromo domain | Chromo domain, conserved site | Chromodomain-helicase-DNA-binding protein 1-like, C-terminal domain | Chromo-like domain superfamily | Helicase, C-terminal domain-like | Helicase superfamily 1/2, ATP-binding domain | P-loop containing nucleoside triphosphate hydrolase | SNF2-like, N-terminal domain superfamily | SNF2, N-terminal | SNF2/RAD5-like, C-terminal helicase domain |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M3B604
|
1778 | ||||||||||||
|
UniProtKB:A0A0R4IC05
|
1693 | ||||||||||||
|
UniProtKB:A0A0R4IAE4
|
1777 |
Interactions and Pathways
No data available
Plasmids
No data available