Gene
pon2
- ID
- ZDB-GENE-030131-7116
- Name
- paraoxonase 2
- Symbol
- pon2 Nomenclature History
- Previous Names
-
- fk84f07
- wu:fk84f07
- zgc:77556
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to have arylesterase activity. Human ortholog(s) of this gene implicated in artery disease (multiple); neurodegenerative disease (multiple); type 2 diabetes mellitus; and vascular dementia. Is expressed in cranium. Orthologous to several human genes including PON2 (paraoxonase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:77556 (2 images)
- IMAGE:6911665 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| {Coronary artery disease, susceptibility to} |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Arylesterase | Nitrous oxide reductase, N-terminal | Six-bladed beta-propeller, TolB-like |
|---|---|---|---|---|
|
UniProtKB:Q6NXA5
|
355 |
Interactions and Pathways
No data available
Plasmids
No data available