Gene
dcxr
- ID
- ZDB-GENE-030131-7002
- Name
- dicarbonyl/L-xylulose reductase
- Symbol
- dcxr Nomenclature History
- Previous Names
-
- wu:fa12f09
- zgc:111977
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to have L-xylulose reductase (NADP+) activity and carbonyl reductase (NADPH) activity. Predicted to be involved in glucose metabolic process and xylulose metabolic process. Human ortholog(s) of this gene implicated in pentosuria. Orthologous to human DCXR (dicarbonyl and L-xylulose reductase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7140405 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| pentosuria | Alliance | [Pentosuria] | 260800 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | L-xylulose reductase/Carbonyl reductase | NAD(P)-binding domain superfamily | Short-chain dehydrogenase/reductase, conserved site | Short-chain dehydrogenase/reductase SDR |
|---|---|---|---|---|---|
|
UniProtKB:Q567K5
|
244 |
Interactions and Pathways
No data available
Plasmids
No data available