Gene
rapgef6
- ID
- ZDB-GENE-030131-6972
- Name
- Rap guanine nucleotide exchange factor (GEF) 6
- Symbol
- rapgef6 Nomenclature History
- Previous Names
-
- wu:fa12b02
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to have guanyl-nucleotide exchange factor activity. Predicted to be involved in small GTPase mediated signal transduction. Orthologous to human RAPGEF6 (Rap guanine nucleotide exchange factor 6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000159 | Ras-associating domain |
| Domain | IPR000595 | Cyclic nucleotide-binding domain |
| Domain | IPR000651 | Ras-like guanine nucleotide exchange factor, N-terminal |
| Domain | IPR001478 | PDZ domain |
| Domain | IPR001895 | Ras guanine-nucleotide exchange factors catalytic domain |
| Homologous_superfamily | IPR014710 | RmlC-like jelly roll fold |
| Homologous_superfamily | IPR018490 | Cyclic nucleotide-binding domain superfamily |
| Homologous_superfamily | IPR023578 | Ras guanine nucleotide exchange factor domain superfamily |
| Homologous_superfamily | IPR036034 | PDZ superfamily |
| Homologous_superfamily | IPR036964 | Ras guanine-nucleotide exchange factor, catalytic domain superfamily |
Domain Details Per Protein
| Protein | Length | Cyclic nucleotide-binding domain | Cyclic nucleotide-binding domain superfamily | PDZ domain | PDZ superfamily | Ras-associating domain | Ras guanine-nucleotide exchange factor, catalytic domain superfamily | Ras guanine nucleotide exchange factor domain superfamily | Ras guanine-nucleotide exchange factors catalytic domain | Ras-like guanine nucleotide exchange factor, N-terminal | RmlC-like jelly roll fold |
|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M6Z3X1
|
1546 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available