Gene

myo1b

ID

ZDB-GENE-030131-695

Name

myosin IB

Symbol

myo1b Nomenclature History

Previous Names

myo1b2 (1)
myo1bl1 (1)
myo1bl2 (1)
si:busm1-60j23.1
wu:fb39h10 (1)
wu:fc46c09
zgc:110446
zgc:113187

Type

protein_coding_gene

Location

Chr: 9 Mapping Details/Browsers

Description

Predicted to enable actin filament binding activity and microfilament motor activity. Predicted to be involved in actin filament organization and vesicle transport along actin filament. Predicted to be part of myosin complex. Predicted to be active in several cellular components, including actin cytoskeleton; brush border; and microvillus. Is expressed in dorsolateral placode; lens; notochord; rhombomere; and somite. Orthologous to human MYO1B (myosin IB).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

4 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:110446 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Diz-Munoz et al., 2010
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With myo1b Human Ortholog

No data available

Associated With myo1b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Binding_site	IPR000048	IQ motif, EF-hand binding site
Domain	IPR010926	Class I myosin tail homology domain
Domain	IPR036072	Class I myosin, motor domain
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily	IPR036961	Kinesin motor domain superfamily

Domain Details Per Protein

Protein	Length	Class I myosin, motor domain	Class I myosin tail homology domain	IQ motif, EF-hand binding site	Kinesin motor domain superfamily	P-loop containing nucleoside triphosphate hydrolase
UniProtKB:A0A8M3B2K3 InterPro	1138
UniProtKB:A0A8M2BFG0 InterPro	1080
UniProtKB:A0A8M2BFD8 InterPro	1109
UniProtKB:A0A8M1RIU5 InterPro	1165
UniProtKB:A0A8M3B5I5 InterPro	1138
UniProtKB:A0A8M2BG11 InterPro	1167
UniProtKB:A0A8M3AVX4 InterPro	1136
UniProtKB:A0A8M2BFF2 InterPro	1109
UniProtKB:A0A8M1QLB6 InterPro	1078
UniProtKB:F1R617 InterPro	1107

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	myo1b-201 (1) Ensembl	Ensembl	772 nt	Select Tool ZFIN BLAST
mRNA	myo1b-203 (1) Ensembl	Ensembl	993 nt	Select Tool ZFIN BLAST
mRNA	myo1b-204 (1) Ensembl	Ensembl	5,429 nt	Select Tool ZFIN BLAST
mRNA	myo1b-206 (1) Ensembl	Ensembl	425 nt	Select Tool ZFIN BLAST
mRNA	myo1b-207 (1) Ensembl	Ensembl	501 nt	Select Tool ZFIN BLAST
mRNA	ottdart00000002373 (1)	Havana	3,355 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	myo1b-002 (1) Ensembl	Ensembl	777 nt	Select Tool ZFIN BLAST
ncRNA	myo1b-005 (1) Ensembl	Ensembl	643 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations