Gene

trmt2a

ID
ZDB-GENE-030131-6876
Name
tRNA methyltransferase 2 homolog A
Symbol
trmt2a Nomenclature History
Previous Names
  • fa10b06
  • htf9c (1)
  • wu:fa10b06
  • zgc:55519
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have RNA binding activity and RNA methyltransferase activity. Predicted to be involved in RNA processing and methylation. Is expressed in several structures, including cerebellum; digestive system; midbrain; pectoral fin musculature; and retina. Orthologous to human TRMT2A (tRNA methyltransferase 2 homolog A).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With trmt2a Human Ortholog
No data available
Associated With trmt2a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR030390 RNA methyltransferase TrmA, active site
Domain IPR000504 RNA recognition motif domain
Domain IPR034262 TRMT2A, RNA recognition motif
Family IPR010280 (Uracil-5)-methyltransferase family
Family IPR045850 tRNA (uracil(54)-C(5))-methyltransferase, metazoa type
Homologous_superfamily IPR012677 Nucleotide-binding alpha-beta plait domain superfamily
Homologous_superfamily IPR029063 S-adenosyl-L-methionine-dependent methyltransferase superfamily
Homologous_superfamily IPR035979 RNA-binding domain superfamily
Domain Details Per Protein
Protein Length Nucleotide-binding alpha-beta plait domain superfamily RNA-binding domain superfamily RNA methyltransferase TrmA, active site RNA recognition motif domain S-adenosyl-L-methionine-dependent methyltransferase superfamily TRMT2A, RNA recognition motif tRNA (uracil(54)-C(5))-methyltransferase, metazoa type (Uracil-5)-methyltransferase family
UniProtKB:Q7ZVY1 619
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA trmt2a-201 (1) Ensembl 2,095 nt
mRNA trmt2a-203 (1) Ensembl 2,192 nt
ncRNA trmt2a-002 (1) Ensembl 732 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations