Gene
picalmb
- ID
- ZDB-GENE-030131-6795
- Name
- phosphatidylinositol binding clathrin assembly protein b
- Symbol
- picalmb Nomenclature History
- Previous Names
-
- picalm
- picalml
- fa01d03
- wu:fa01d03 (1)
- wu:fa05d03
- wu:fb69g01
- wu:fe17e02
- zgc:91993
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to have SNARE binding activity; clathrin heavy chain binding activity; and phosphatidylinositol binding activity. Predicted to be involved in clathrin-dependent endocytosis and synaptic vesicle budding from presynaptic endocytic zone membrane. Predicted to localize to clathrin-coated pit; cytoplasmic vesicle; and extrinsic component of presynaptic endocytic zone membrane. Human ortholog(s) of this gene implicated in acute myeloid leukemia. Orthologous to human PICALM (phosphatidylinositol binding clathrin assembly protein).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 2 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
acute myeloid leukemia | Alliance | Leukemia, acute myeloid, somatic | 601626 |
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | ANTH domain superfamily | AP180 N-terminal homology (ANTH) domain | Clathrin coat assembly protein AP180-like | ENTH domain | ENTH/VHS |
---|---|---|---|---|---|---|
UniProtKB:A0A8M3APS6
|
651 | |||||
UniProtKB:Q6AXI5
|
590 | |||||
UniProtKB:A0A8M3B104
|
701 | |||||
UniProtKB:A0A8M6ZA05
|
702 | |||||
UniProtKB:A0A8M3APR9
|
729 | |||||
UniProtKB:A0A8M6Z9M1
|
730 | |||||
UniProtKB:A0A8M3B110
|
616 | |||||
UniProtKB:A0A8M3AHC4
|
621 | |||||
UniProtKB:A0A8M3ASP1
|
672 | |||||
UniProtKB:A0A8M3AIH0
|
667 | |||||
UniProtKB:A0A8M3AIG6
|
700 | |||||
UniProtKB:A0A8M3AHB8
|
725 | |||||
UniProtKB:A0A8M6Z2V9
|
726 | |||||
UniProtKB:A0A8M6Z4D6
|
704 |
Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
picalmb-203
(1)
|
Ensembl | 1,634 nt | ||
mRNA |
picalmb-205
(1)
|
Ensembl | 4,903 nt | ||
mRNA |
picalmb-206
(1)
|
Ensembl | 5,105 nt | ||
ncRNA |
picalmb-002
(1)
|
Ensembl | 627 nt | ||
ncRNA |
picalmb-003
(1)
|
Ensembl | 537 nt | ||
ncRNA |
picalmb-004
(1)
|
Ensembl | 161 nt |
Interactions and Pathways
No data available
Plasmids
No data available