Gene
map4k4
- ID
- ZDB-GENE-030131-6722
- Name
- mitogen-activated protein kinase kinase kinase kinase 4
- Symbol
- map4k4 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to enable ATP binding activity and protein serine/threonine kinase activity. Predicted to be involved in regulation of cell communication and regulation of signaling. Predicted to act upstream of or within protein phosphorylation. Human ortholog(s) of this gene implicated in hepatocellular carcinoma and lung adenocarcinoma. Orthologous to human MAP4K4 (mitogen-activated protein kinase kinase kinase kinase 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Citron homology (CNH) domain | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site | STE20 Ser/Thr Protein Kinase |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9QB07 | InterPro | 930 | |||||
| UniProtKB:A0A8M9QFN8 | InterPro | 1006 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
map4k4-201
(1)
|
Ensembl | 3,759 nt | ||
| mRNA |
map4k4-202
(1)
|
Ensembl | 5,045 nt |
Interactions and Pathways
No data available
Plasmids
No data available