Gene

map4k4

ID
ZDB-GENE-030131-6722
Name
mitogen-activated protein kinase kinase kinase kinase 4
Symbol
map4k4 Nomenclature History
Previous Names
  • fa03e11
  • msn2 (1)
  • si:zfos-433a6.1 (1)
  • wu:fa03e11 (1)
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Predicted to have protein serine/threonine kinase activity. Predicted to be involved in several processes, including activation of protein kinase activity; signal transduction by protein phosphorylation; and stress-activated protein kinase signaling cascade. Predicted to localize to cytoplasm. Orthologous to human MAP4K4 (mitogen-activated protein kinase kinase kinase kinase 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With map4k4 Human Ortholog
No data available
Associated With map4k4 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Domain IPR000719 Protein kinase domain
Domain IPR001180 Citron homology (CNH) domain
Family IPR051700 STE20 Ser/Thr Protein Kinase
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Domain Details Per Protein
Protein Length Citron homology (CNH) domain Protein kinase domain Protein kinase-like domain superfamily Serine/threonine-protein kinase, active site STE20 Ser/Thr Protein Kinase
UniProtKB:A0A8M9QB07 930
UniProtKB:A0A8M9QFN8 1006
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA map4k4-201 (1) Ensembl 3,759 nt
mRNA map4k4-202 (1) Ensembl 5,045 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations