ZFIN is now using GRCz12tu for Genomic Data
Gene
zfhx2
- ID
- ZDB-GENE-030131-6699
- Name
- zinc finger homeobox 2
- Symbol
- zfhx2 Nomenclature History
- Previous Names
-
- wu:fa03a11
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in Marsili syndrome. Orthologous to human ZFHX2 (zinc finger homeobox 2).
- Genome Resources
-
- Alliance (1)
- Gene:795005 (1)
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Marsili syndrome | Alliance | ?Marsili syndrome | 147430 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017970 | Homeobox, conserved site |
| Domain | IPR001356 | Homeodomain |
| Domain | IPR013087 | Zinc finger C2H2-type |
| Family | IPR051968 | Zinc finger homeobox transcription regulators |
| Homologous_superfamily | IPR009057 | Homedomain-like superfamily |
| Homologous_superfamily | IPR036236 | Zinc finger C2H2 superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Homedomain-like superfamily | Homeobox, conserved site | Homeodomain | Zinc finger C2H2 superfamily | Zinc finger C2H2-type | Zinc finger homeobox transcription regulators |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M1PYY4 | InterPro | 1529 | ||||||
| UniProtKB:A0A8M9PUD5 | InterPro | 1512 | ||||||
| UniProtKB:A0AC58IRE4 | InterPro | 1512 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers
- Comparative Orthology
- Alliance