Gene
eef1db
- ID
- ZDB-GENE-030131-6544
- Name
- eukaryotic translation elongation factor 1 delta b (guanine nucleotide exchange protein)
- Symbol
- eef1db Nomenclature History
- Previous Names
-
- im:7233939
- si:dkey-235d18.4
- wu:fa14f09
- zgc:114052
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in translational elongation. Predicted to act upstream of or within translation. Predicted to be part of eukaryotic translation elongation factor 1 complex. Predicted to be active in cytosol. Orthologous to human EEF1D (eukaryotic translation elongation factor 1 delta).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Neurodevelopmental disorder with thin corpus callosum, hypotonia, and absent language | 621150 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR001326 | Translation elongation factor EF1B, beta/delta chains, conserved site |
| Domain | IPR014038 | Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain |
| Domain | IPR018940 | Elongation factor 1 beta central acidic region, eukaryote |
| Family | IPR049720 | Translation elongation factor EF1B, beta/delta subunit |
| Homologous_superfamily | IPR014717 | Translation elongation factor EF1B/small ribosomal subunit protein bS6 |
| Homologous_superfamily | IPR036219 | Translation elongation factor eEF-1beta-like superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Elongation factor 1 beta central acidic region, eukaryote | Translation elongation factor eEF-1beta-like superfamily | Translation elongation factor EF1B, beta/delta chains, conserved site | Translation elongation factor EF1B, beta/delta subunit | Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain | Translation elongation factor EF1B/small ribosomal subunit protein bS6 |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M2B7W1 | InterPro | 578 | ||||||
| UniProtKB:A0A8M2B7V6 | InterPro | 554 | ||||||
| UniProtKB:Q5SPD1 | InterPro | 274 | ||||||
| UniProtKB:Q5SPD0 | InterPro | 298 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
eef1db-201
(1)
|
Ensembl | 1,042 nt | ||
| mRNA |
eef1db-202
(1)
|
Ensembl | 988 nt | ||
| mRNA |
eef1db-203
(1)
|
Ensembl | 830 nt | ||
| mRNA |
eef1db-204
(1)
|
Ensembl | 661 nt | ||
| mRNA |
eef1db-205
(1)
|
Ensembl | 661 nt | ||
| mRNA |
eef1db-206
(1)
|
Ensembl | 804 nt |
Interactions and Pathways
No data available
Plasmids
No data available