ZFIN ID: ZDB-GENE-030131-6385
Gene Name: activity-dependent neuroprotector homeobox b
Gene Symbol: adnpb    Nomenclature History

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Previous Names: adnp1b (1), adnp, wu:fi72f04

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 23 Mapping Details/Browsers
Description: Predicted to have DNA binding activity and metal ion binding activity. Involved in erythrocyte maturation. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in Helsmoortel-Van Der Aa Syndrome. Orthologous to human ADNP (activity dependent neuroprotector homeobox).
Genome Resources: Alliance (1),  Gene:100330315 (1),  Ensembl(GRCz11):ENSDARG00000074293 (2)
GENE EXPRESSION
All Expression Data: Fig. S3 from Dresner et al., 2012
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-adnpb N/A 1
DISEASE ASSOCIATED WITH adnpb HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Helsmoortel-Van Der Aa Syndrome Alliance Helsmoortel-van der Aa syndrome 615873
DISEASE ASSOCIATED WITH adnpb VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process erythrocyte maturation (more)
Cellular Component nucleus (more)
Molecular Function DNA binding (more)
GO Terms (all 4)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA adnpb-201 (1)    Ensembl 3636
Browsers: UCSCEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM adnpb No data available
MARKER RELATIONSHIPS
adnpb Contained in: [BAC] CH211-104F13 (1), DKEYP-97F4
adnpb Encodes: [EST] fi72f04, wz11485, wz13160
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001347570 (1)
Genomic GenBank:CR318627 176131 nt
Select Tool
Polypeptide UniProtKB:A0A2R8RLW7 (1) 1003 aa
Sequence Information (all 16)
ORTHOLOGY for adnpb ( Chr: 23 )
CITATIONS (18)