ZFIN is now using GRCz12tu for Genomic Data
Gene
arid2
- ID
- ZDB-GENE-030131-6311
- Name
- AT-rich interactive domain 2
- Symbol
- arid2 Nomenclature History
- Previous Names
-
- fi45a01
- si:ch211-132p20.1
- wu:fi45a01
- zgc:152901
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable DNA binding activity. Predicted to be involved in chromatin remodeling. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be part of brahma complex. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome 6; colorectal cancer; and hepatocellular carcinoma. Orthologous to human ARID2 (AT-rich interaction domain 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Coffin-Siris syndrome 6 | Alliance | Coffin-Siris syndrome 6 | 617808 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001606 | ARID DNA-binding domain |
| Domain | IPR003150 | DNA-binding RFX-type winged-helix domain |
| Domain | IPR013087 | Zinc finger C2H2-type |
| Family | IPR052406 | Chromatin Remodeling Complex Component |
| Homologous_superfamily | IPR011989 | Armadillo-like helical |
| Homologous_superfamily | IPR016024 | Armadillo-type fold |
| Homologous_superfamily | IPR036388 | Winged helix-like DNA-binding domain superfamily |
| Homologous_superfamily | IPR036390 | Winged helix DNA-binding domain superfamily |
| Homologous_superfamily | IPR036431 | ARID DNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | ARID DNA-binding domain | ARID DNA-binding domain superfamily | Armadillo-like helical | Armadillo-type fold | Chromatin Remodeling Complex Component | DNA-binding RFX-type winged-helix domain | Winged helix DNA-binding domain superfamily | Winged helix-like DNA-binding domain superfamily | Zinc finger C2H2-type |
|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:F6NXG0 | InterPro | 1572 | |||||||||
| UniProtKB:A0JPE6 | InterPro | 1570 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers