Gene

fbxw11a

ID

ZDB-GENE-030131-6305

Name

F-box and WD repeat domain containing 11a

Symbol

fbxw11a Nomenclature History

Previous Names

btrc2
fbxw11
wu:fd14d12 (1)
wu:fi43f07

Type

protein_coding_gene

Location

Chr: 14 Mapping Details/Browsers

Description

Predicted to have snoRNA binding activity. Involved in sprouting angiogenesis. Predicted to localize to small-subunit processome. Orthologous to human FBXW11 (F-box and WD repeat domain containing 11).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

5 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:55481 (1 image)
IMAGE:6912104 (1 image)
IMAGE:7147071 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With fbxw11a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Neurodevelopmental, jaw, eye, and digital syndrome	618914

Associated With fbxw11a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR019775	WD40 repeat, conserved site
Domain	IPR001810	F-box domain
Domain	IPR021977	D domain of beta-TrCP
Family	IPR050995	WD repeat and F-box domain-containing protein
Homologous_superfamily	IPR015943	WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily	IPR036047	F-box-like domain superfamily
Homologous_superfamily	IPR036322	WD40-repeat-containing domain superfamily
Repeat	IPR001680	WD40 repeat
Repeat	IPR020472	G-protein beta WD-40 repeat

Domain Details Per Protein

Protein	Length	D domain of beta-TrCP	F-box domain	F-box-like domain superfamily	G-protein beta WD-40 repeat	WD40 repeat	WD40 repeat, conserved site	WD40-repeat-containing domain superfamily	WD40/YVTN repeat-like-containing domain superfamily	WD repeat and F-box domain-containing protein
UniProtKB:A0A2R8QFQ6 InterPro	562
UniProtKB:A0A8M9QAY3 InterPro	483

Transcripts

Genome Browsers

NCBI

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	fbxw11a-201 (1) Ensembl	Ensembl		3,089 nt	Select Tool ZFIN BLAST
mRNA	fbxw11a-202 (1) Ensembl	Ensembl		3,194 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations