Gene
fbxw11a
- ID
- ZDB-GENE-030131-6305
- Name
- F-box and WD repeat domain containing 11a
- Symbol
- fbxw11a Nomenclature History
- Previous Names
-
- btrc2
- fbxw11
- wu:fd14d12 (1)
- wu:fi43f07
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to enable snoRNA binding activity. Acts upstream of or within sprouting angiogenesis. Predicted to be located in cytoplasm and nucleus. Predicted to be part of small-subunit processome. Is expressed in brain; head mesenchyme; and retina. Orthologous to human FBXW11 (F-box and WD repeat domain containing 11).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Neurodevelopmental, jaw, eye, and digital syndrome | 618914 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR019775 | WD40 repeat, conserved site |
| Domain | IPR001810 | F-box domain |
| Domain | IPR021977 | D domain of beta-TrCP |
| Family | IPR050995 | WD repeat and F-box domain-containing protein |
| Homologous_superfamily | IPR015943 | WD40/YVTN repeat-like-containing domain superfamily |
| Homologous_superfamily | IPR036047 | F-box-like domain superfamily |
| Homologous_superfamily | IPR036322 | WD40-repeat-containing domain superfamily |
| Repeat | IPR001680 | WD40 repeat |
| Repeat | IPR020472 | G-protein beta WD-40 repeat |
Domain Details Per Protein
| Protein | Additional Resources | Length | D domain of beta-TrCP | F-box domain | F-box-like domain superfamily | G-protein beta WD-40 repeat | WD40 repeat | WD40 repeat, conserved site | WD40-repeat-containing domain superfamily | WD40/YVTN repeat-like-containing domain superfamily | WD repeat and F-box domain-containing protein |
|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A2R8QFQ6 | InterPro | 562 | |||||||||
| UniProtKB:A0A8M9QAY3 | InterPro | 483 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
fbxw11a-201
(1)
|
Ensembl | 3,089 nt | ||
| mRNA |
fbxw11a-202
(1)
|
Ensembl | 3,194 nt |
Interactions and Pathways
No data available
Plasmids
No data available