Gene
sh3rf1
- ID
- ZDB-GENE-030131-6288
- Name
- SH3 domain containing ring finger 1
- Symbol
- sh3rf1 Nomenclature History
- Previous Names
-
- fi42f11
- si:ch211-114c9.2
- si:dkey-15j16.4
- wu:fi42f11
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to have MAP-kinase scaffold activity and ubiquitin protein ligase activity. Predicted to be involved in several processes, including positive regulation of JNK cascade; protein autoubiquitination; and regulation of alpha-beta T cell activation. Predicted to localize to lamellipodium. Orthologous to several human genes including SH3RF1 (SH3 domain containing ring finger 1).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Conserved_site | IPR017907 | Zinc finger, RING-type, conserved site |
Domain | IPR001452 | SH3 domain |
Domain | IPR001841 | Zinc finger, RING-type |
Domain | IPR027370 | Zinc finger, RING-type, eukaryotic |
Domain | IPR035795 | E3 ubiquitin-protein ligase SH3RF1, second SH3 domain |
Domain | IPR035816 | SH3RF1/SH3RF3, fourth SH3 domain |
Family | IPR050384 | Endophilin/SH3RF |
Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
Homologous_superfamily | IPR036028 | SH3-like domain superfamily |
Domain Details Per Protein
Protein | Length | E3 ubiquitin-protein ligase SH3RF1, second SH3 domain | Endophilin/SH3RF | SH3 domain | SH3-like domain superfamily | SH3RF1/SH3RF3, fourth SH3 domain | Zinc finger, RING/FYVE/PHD-type | Zinc finger, RING-type | Zinc finger, RING-type, conserved site | Zinc finger, RING-type, eukaryotic |
---|---|---|---|---|---|---|---|---|---|---|
UniProtKB:B3DIT8
|
880 | |||||||||
UniProtKB:A5D8S5
|
867 | |||||||||
UniProtKB:A0A8M1N9B8
|
857 |
Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
sh3rf1-201
(1)
|
Ensembl | 4,714 nt |
Interactions and Pathways
No data available
Plasmids
No data available