Gene

kdm4ab

ID

ZDB-GENE-030131-6279

Name

lysine (K)-specific demethylase 4A, genome duplicate b

Symbol

kdm4ab Nomenclature History

Previous Names

jmjd2A (1)
jmjd2al
si:ch211-262l3.1
wu:fi42b08

Type

protein_coding_gene

Location

Chr: 2 Mapping Details/Browsers

Description

Predicted to enable histone H3K36 demethylase activity and histone H3K9 demethylase activity. Acts upstream of or within blood vessel morphogenesis. Predicted to be active in nucleus. Orthologous to human KDM4A (lysine demethylase 4A).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With kdm4ab Human Ortholog

No data available

Associated With kdm4ab Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001965	Zinc finger, PHD-type
Domain	IPR002999	Tudor domain
Domain	IPR003347	JmjC domain
Domain	IPR003349	JmjN domain
Domain	IPR019787	Zinc finger, PHD-finger
Domain	IPR034732	Extended PHD (ePHD) domain
Domain	IPR040477	Lysine-specific demethylase 4-like, Tudor domain
Domain	IPR047481	Lysine-specific demethylase 4A, second Tudor domain
Domain	IPR047482	Lysine-specific demethylase 4A, extended PHD finger
Homologous_superfamily	IPR011011	Zinc finger, FYVE/PHD-type
Homologous_superfamily	IPR013083	Zinc finger, RING/FYVE/PHD-type

Domain Details Per Protein

Protein	Length	Extended PHD (ePHD) domain	JmjC domain	JmjN domain	Lysine-specific demethylase 4A, extended PHD finger	Lysine-specific demethylase 4A, second Tudor domain	Lysine-specific demethylase 4-like, Tudor domain	Tudor domain	Zinc finger, FYVE/PHD-type	Zinc finger, PHD-finger	Zinc finger, PHD-type	Zinc finger, RING/FYVE/PHD-type
UniProtKB:F1QNG0 InterPro	1045

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	kdm4ab-201 (1) Ensembl	Ensembl		4,339 nt	Select Tool ZFIN BLAST
mRNA	kdm4ab-202 (1) Ensembl	Ensembl		3,490 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations