ZFIN ID: ZDB-GENE-030131-6244
Gene Name: zinc finger protein 644a
Gene Symbol: znf644a    Nomenclature History

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Previous Names: znf644, fi40c02, si:ch211-83f14.4, wu:fi40c02

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 2 Mapping Details/Browsers
Description: Predicted to have DNA-binding transcription factor activity. Involved in camera-type eye photoreceptor cell differentiation and regulation of gene silencing. Predicted to localize to nucleus. Is expressed in head; midbrain; optic cup; presumptive retinal pigmented epithelium; and trunk. Human ortholog(s) of this gene implicated in myopia. Orthologous to human ZNF644 (zinc finger protein 644).
Genome Resources: Alliance (1),  Gene:100007441 (1),  Ensembl(GRCz11):ENSDARG00000101361 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la028762Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa30817 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa39815 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa39816 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa39817 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-znf644a N/A 1
    DISEASE ASSOCIATED WITH znf644a HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    myopia Alliance Myopia 21, autosomal dominant 614167
    DISEASE ASSOCIATED WITH znf644a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process camera-type eye photoreceptor cell differentiation (more)
    Cellular Component nucleus (more)
    Molecular Function metal ion binding (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA znf644a-201 (1)    Ensembl 4411
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM znf644a No data available
    MARKER RELATIONSHIPS
    znf644a Contained in: [BAC] CH211-83F14 (1)
    znf644a Contains: [SNP] rs3727631 (1)
    znf644a Encodes: [EST] fi40c02
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001278254 (1)
    Genomic GenBank:BX927353 (1) 94558 nt
    Select Tool
    Polypeptide UniProtKB:A2BIH4 (1) 1169 aa
    Sequence Information (all 8)
    ORTHOLOGY for znf644a ( Chr: 2 )
    CITATIONS (19)