Gene

mlst8

ID

ZDB-GENE-030131-6176

Name

MTOR associated protein, LST8 homolog (S. cerevisiae)

Symbol

mlst8 Nomenclature History

Previous Names

fi37e04
gbl
wu:fi37e04 (1)
zgc:55455 (1)
zgc:85668 (1)

Type

protein_coding_gene

Location

Chr: 12 Mapping Details/Browsers

Description

Predicted to be involved in TOR signaling and regulation of actin cytoskeleton organization. Predicted to be located in cytoplasm. Predicted to be part of TORC1 complex and TORC2 complex. Orthologous to human MLST8 (MTOR associated protein, LST8 homolog).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:55455 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With mlst8 Human Ortholog

No data available

Associated With mlst8 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR019775	WD40 repeat, conserved site
Family	IPR037588	Target of rapamycin complex subunit LST8
Homologous_superfamily	IPR011047	Quinoprotein alcohol dehydrogenase-like superfamily
Homologous_superfamily	IPR015943	WD40/YVTN repeat-like-containing domain superfamily
Repeat	IPR001680	WD40 repeat

Domain Details Per Protein

Protein	Length	Quinoprotein alcohol dehydrogenase-like superfamily	Target of rapamycin complex subunit LST8	WD40 repeat	WD40 repeat, conserved site	WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:Q803V5 InterPro	326
UniProtKB:B2GPI2 InterPro	326

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	mlst8-201 (1) Ensembl	Ensembl	1,961 nt	Select Tool ZFIN BLAST
mRNA	mlst8-203 (1) Ensembl	Ensembl	871 nt	Select Tool ZFIN BLAST
mRNA	mlst8-204 (1) Ensembl	Ensembl	2,618 nt	Select Tool ZFIN BLAST
mRNA	mlst8-205 (1) Ensembl	Ensembl	1,002 nt	Select Tool ZFIN BLAST
mRNA	mlst8-206 (1) Ensembl	Ensembl	1,961 nt	Select Tool ZFIN BLAST
mRNA	mlst8-207 (1) Ensembl	Ensembl	2,107 nt	Select Tool ZFIN BLAST
ncRNA	mlst8-002 (1) Ensembl	Ensembl	584 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations