Gene

psmd12

ID
ZDB-GENE-030131-617
Name
proteasome 26S subunit, non-ATPase 12
Symbol
psmd12 Nomenclature History
Previous Names
  • fc34f08
  • wu:fb38a06
  • wu:fc34f08
  • wu:fc49f02
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Involved in brain development; cranial skeletal system development; and kidney development. Predicted to localize to cytoplasm; nuclear proteasome complex; and proteasome regulatory particle, lid subcomplex. Orthologous to human PSMD12 (proteasome 26S subunit, non-ATPase 12).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Küry et al., 2017
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With psmd12 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Stankiewicz-Isidor syndrome 617516
Associated With psmd12 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000717 Proteasome component (PCI) domain
Domain IPR040896 26S proteasome regulatory subunit RPN5, C-terminal domain
Family IPR040134 26S Proteasome non-ATPase regulatory subunit 12/COP9 signalosome complex subunit 4
Homologous_superfamily IPR036388 Winged helix-like DNA-binding domain superfamily
Homologous_superfamily IPR036390 Winged helix DNA-binding domain superfamily
Domain Details Per Protein
Protein Length 26S Proteasome non-ATPase regulatory subunit 12/COP9 signalosome complex subunit 4 26S proteasome regulatory subunit RPN5, C-terminal domain Proteasome component (PCI) domain Winged helix DNA-binding domain superfamily Winged helix-like DNA-binding domain superfamily
UniProtKB:Q8AW07 456
Transcripts
Genome Browsers
Type Name Annotation Method Length (nt) Analysis
mRNA psmd12-201 (1) Havana 2342 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations