Gene

osbpl2b

ID
ZDB-GENE-030131-6138
Name
oxysterol binding protein-like 2b
Symbol
osbpl2b Nomenclature History
Previous Names
  • osbpl2
  • wu:fi36a04
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Description
Predicted to enable cholesterol binding activity and sterol transporter activity. Predicted to act upstream of or within lipid transport. Predicted to be active in cytosol; intracellular membrane-bounded organelle; and membrane. Is expressed in several structures, including blastodisc; digestive system; nervous system; otic vesicle; and yolk syncytial layer. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 67. Orthologous to human OSBPL2 (oxysterol binding protein like 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
13 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With osbpl2b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal dominant nonsyndromic deafness 67 Alliance Deafness, autosomal dominant 67 616340
Associated With osbpl2b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018494 Oxysterol-binding protein, conserved site
Family IPR000648 Oxysterol-binding protein
Homologous_superfamily IPR037239 Oxysterol-binding protein superfamily
Domain Details Per Protein
Protein Length Oxysterol-binding protein Oxysterol-binding protein, conserved site Oxysterol-binding protein superfamily
UniProtKB:E9QJF0 198
UniProtKB:Q6TLH5 470
UniProtKB:E9QFC0 124
UniProtKB:E7F173 469
UniProtKB:Q7ZVL1 472
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations