Gene
baz1a
- ID
- ZDB-GENE-030131-6105
- Name
- bromodomain adjacent to zinc finger domain, 1A
- Symbol
- baz1a Nomenclature History
- Previous Names
-
- fi34e04
- im:6907928
- wu:fi34e04
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to enable metal ion binding activity. Predicted to act upstream of or within chromatin remodeling. Predicted to be located in nucleus. Orthologous to human BAZ1A (bromodomain adjacent to zinc finger domain 1A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6907928 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa9543 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa11550 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa14102 | Allele with one point mutation | Unknown | Splice Site | ENU | |
| sa32127 | Allele with one point mutation | Unknown | Missense, Splice Site | ENU | |
| sa42873 | Allele with one point mutation | Unknown | Premature Stop | ENU |
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Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Bromodomain | Bromodomain adjacent to zinc finger domain protein 1A | Bromodomain, conserved site | Bromodomain-like superfamily | DDT domain | WHIM1 domain | WHIM2 domain | WSTF/Acf1/Cbp146 | Zinc finger, FYVE/PHD-type | Zinc finger, PHD-finger | Zinc finger, PHD-type | Zinc finger, PHD-type, conserved site | Zinc finger, RING/FYVE/PHD-type | Zinc finger, RING-type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M6YTY8 | InterPro | 1469 | ||||||||||||||
| UniProtKB:A0AB13A3K8 | InterPro | 1469 | ||||||||||||||
| UniProtKB:A0AB13A7N8 | InterPro | 1470 |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH73-32G17 | ZFIN Curated Data | |
| Contained in | BAC | DKEY-71B9 | ||
| Encodes | EST | fi34e04 | ||
| Encodes | EST | IMAGE:6907928 | Thisse et al., 2004 | |
| Has Artifact | EST | fc16e08 |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001365143 (1) | 5422 nt | ||
| Genomic | GenBank:BX088587 (1) | 154682 nt | ||
| Polypeptide | UniProtKB:A0AB13A7N8 (1) | 1470 aa |
- Comparative Orthology
- Alliance
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Briolat, V., Jouneau, L., Carvalho, R., Palha, N., Langevin, C., Herbomel, P., Schwartz, O., Spaink, H.P., Levraud, J.P., Boudinot, P. (2014) Contrasted Innate Responses to Two Viruses in Zebrafish: Insights into the Ancestral Repertoire of Vertebrate IFN-Stimulated Genes. Journal of immunology (Baltimore, Md. : 1950). 192:4328-41
- Huang, H.T., Kathrein, K.L., Barton, A., Gitlin, Z., Huang, Y.H., Ward, T.P., Hofmann, O., Dibiase, A., Song, A., Tyekucheva, S., Hide, W., Zhou, Y., and Zon, L.I. (2013) A network of epigenetic regulators guides developmental haematopoiesis in vivo. Nature cell biology. 15(12):1516-1525
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