Gene

il11ra

ID

ZDB-GENE-030131-5942

Name

interleukin 11 receptor subunit alpha

Symbol

il11ra Nomenclature History

Previous Names

fi26e06
wu:fi26e06

Type

protein_coding_gene

Location

Chr: 10 Mapping Details/Browsers

Description

Predicted to have interleukin-11 binding activity and interleukin-11 receptor activity. Predicted to be involved in positive regulation of cell population proliferation. Predicted to localize to external side of plasma membrane and receptor complex. Is expressed in cranium and frontal-parietal joint. Orthologous to human IL11RA (interleukin 11 receptor subunit alpha).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

5 figures from 5 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

cssl:d199 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With il11ra Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Craniosynostosis and dental anomalies	614188

Associated With il11ra Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR003530	Long hematopoietin receptor, soluble alpha chain, conserved site
Domain	IPR003961	Fibronectin type III
Domain	IPR007110	Immunoglobulin-like domain
Domain	IPR013151	Immunoglobulin-like beta-sandwich domain
Family	IPR050379	Type I Cytokine Receptor
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR036116	Fibronectin type III superfamily
Homologous_superfamily	IPR036179	Immunoglobulin-like domain superfamily