Gene
slc15a2
- ID
- ZDB-GENE-030131-5866
- Name
- solute carrier family 15 member 2
- Symbol
- slc15a2 Nomenclature History
- Previous Names
-
- PEPT2 (1)
- wu:fc84g07
- wu:fi22a10
- zgc:152684
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Enables dipeptide transmembrane transporter activity. Acts upstream of or within response to yeast. Predicted to be located in phagocytic vesicle membrane. Predicted to be active in apical plasma membrane. Is expressed in several structures, including gill; gut; kidney; nervous system; and otic vesicle. Orthologous to human SLC15A2 (solute carrier family 15 member 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | MFS transporter superfamily | Proton-dependent oligopeptide transporter family | PTR2 family proton/oligopeptide symporter, conserved site |
|---|---|---|---|---|
|
UniProtKB:B0S6T2
|
719 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
slc15a2-201
(1)
|
Ensembl | 3,233 nt | ||
| mRNA |
slc15a2-202
(1)
|
Ensembl | 618 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-25L23 | ZFIN Curated Data | |
| Encodes | EST | fc84g07 | ||
| Encodes | EST | fi22a10 | ||
| Encodes | cDNA | MGC:152684 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:192734 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001039828 (1) | 3238 nt | ||
| Genomic | GenBank:BX548071 (1) | 223099 nt | ||
| Polypeptide | UniProtKB:B0S6T2 (1) | 719 aa |
- Vacca, F., Gomes, A.S., Murashita, K., Cinquetti, R., Roseti, C., Barca, A., Rønnestad, I., Verri, T., Bossi, E. (2022) Functional characterization of Atlantic salmon (Salmo salar L.) PepT2 transporters. The Journal of physiology. 600(10):2377-2400
- Meirelles, M.G., Nornberg, B.F., da Silveira, T.L.R., Kütter, M.T., Castro, C.G., Ramirez, J.R.B., Pedrosa, V., Romano, L.A., Marins, L.F. (2021) Growth Hormone Overexpression Induces Hyperphagia and Intestinal Morphophysiological Adaptations to Improve Nutrient Uptake in Zebrafish. Frontiers in Physiology. 12:723853
- Buerger, A.N., Schmidt, J., Chase, A., Paxaio, C., Patel, T.N., Brumback, B.A., Kane, A.S., Martyniuk, C.J., Bisesi, J.H. (2019) Examining the responses of the zebrafish (Danio rerio) gastrointestinal system to the suspected obesogen diethylhexyl phthalate. Environmental pollution (Barking, Essex : 1987). 245:1086-1094
- Barat, A., Sahoo, P.K., Kumar, R., Pande, V. (2016) Solute Carriers (SLCs) identified and characterized from kidney transcriptome of golden mahseer (Tor putitora) (Fam: Cyprinidae). Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. 200:54-61
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Tian, J., He, G., Mai, K., Liu, C. (2015) Effects of postprandial starvation on mRNA expression of endocrine-, amino acid and peptide transporter-, and metabolic enzyme-related genes in zebrafish (Danio rerio). Fish physiology and biochemistry. 41(3):773-87
- Wang, Y.C., Lin, C., Chuang, M.T., Hsieh, W.P., Lan, C.Y., Chuang, Y.J., and Chen, B.S. (2013) Interspecies protein-protein interaction network construction for characterization of host-pathogen interactions: a Candida albicans-zebrafish interaction study. BMC systems biology. 7:79
- Romano, A., Kottra, G., Barca, A., Tiso, N., Maffia, M., Argenton, F., Daniel, H., Storelli, C., and Verri, T. (2006) The high-affinity peptide transporter PEPT2 (SLC15A2) of the zebrafish Danio rerio: functional properties, genomic organization and expression analysis. Physiological Genomics. 24(3):207-217
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
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