Gene
cdc42ep5
- ID
- ZDB-GENE-030131-5813
- Name
- CDC42 effector protein (Rho GTPase binding) 5
- Symbol
- cdc42ep5 Nomenclature History
- Previous Names
-
- cdc42ep1
- cdc42ep1b
- wu:fi19g04
- zgc:153966
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to have GTP-Rho binding activity. Predicted to be involved in Rho protein signal transduction; positive regulation of cellular component organization; and regulation of cell shape. Predicted to localize to cytoplasm; cytoskeleton; and plasma membrane. Is expressed in artery; cardiovascular system; notochord; pharyngeal arch; and polster. Orthologous to human CDC42EP5 (CDC42 effector protein 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6907558 (13 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cdc42 effector-like | Cdc42 Effector Protein BORG/CEP | CRIB domain |
|---|---|---|---|---|
|
UniProtKB:F1R2T1
|
295 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cdc42ep5-201
(1)
|
Ensembl | 1,675 nt | ||
| mRNA |
cdc42ep5-202
(1)
|
Ensembl | 901 nt | ||
| mRNA |
cdc42ep5-203
(1)
|
Ensembl | 896 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance
- Gene Tree
- Ensembl
- Note
- Woods, et al. (2005. Genome Res. 15:1307-1314.) report this gene to be cdc42ep1b based on amino acid similarity to human CDC42EP1. Subsequent analysis suggests it is the ortholog of human CDC42EP5 and mouse Cdc42ep5 based on amino acid similarity and conserved synteny.