Gene

chp2

ID

ZDB-GENE-030131-5810

Name

calcineurin-like EF-hand protein 2

Symbol

chp2 Nomenclature History

Previous Names

wu:fi19e07
zgc:55363 (1)

Type

protein_coding_gene

Location

Chr: 15 Mapping Details/Browsers

Description

Predicted to enable calcium ion binding activity. Predicted to be involved in positive regulation of calcineurin-NFAT signaling cascade. Predicted to act upstream of or within protein transport. Predicted to be located in cytoplasm and nucleus. Predicted to be active in plasma membrane. Orthologous to human CHP2 (calcineurin like EF-hand protein 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

4 figures from 4 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:55363 (1 image)
eu217 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With chp2 Human Ortholog

No data available

Associated With chp2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Binding_site	IPR018247	EF-Hand 1, calcium-binding site
Domain	IPR002048	EF-hand domain
Family	IPR051875	Calcineurin B homologous
Homologous_superfamily	IPR011992	EF-hand domain pair

Domain Details Per Protein

Protein	Length	Calcineurin B homologous	EF-Hand 1, calcium-binding site	EF-hand domain	EF-hand domain pair
UniProtKB:Q803Y0 InterPro	195

Transcripts

Genome Browsers

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	chp2-201 (1) Ensembl	Ensembl		1,879 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl
Note: Woods, et al. (2005. Genome Res. 15:1307-1314.) name this gene chp and report orthology to human CHP. Subsequent analysis suggest this zebrafish gene is the ortholog of human CHP2.

Citations