Gene

rbmx

ID

ZDB-GENE-030131-579

Name

RNA binding motif protein X-linked

Symbol

rbmx Nomenclature History

Previous Names

fc66e11 (1)
wu:fb37c07 (1)
wu:fc66e11 (1)

Type

protein_coding_gene

Location

Chr: 14 Mapping Details/Browsers

Description

Predicted to have chromatin binding activity and nucleic acid binding activity. Predicted to be involved in several processes, including RNA metabolic process; cellular response to interleukin-1; and regulation of mRNA splicing, via spliceosome. Predicted to localize to extracellular exosome and nucleus. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability Shashi type. Is expressed in several structures, including brain; digestive system; immature eye; notochord; and retinal ganglion cell layer. Orthologous to several human genes including RBMX (RNA binding motif protein X-linked).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

12 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:56625 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With rbmx Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
syndromic X-linked intellectual disability Shashi type	Alliance	?Intellectual developmental disorder, X-linked syndromic, Shashi type	300238
X-linked mental retardation Gustavson type	Alliance	?Intellectual developmental disorder, X-linked syndromic, Gustavson type	309555

Associated With rbmx Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000504	RNA recognition motif domain
Domain	IPR003954	RNA recognition motif domain, eukaryote
Domain	IPR012604	RBM1CTR
Family	IPR050441	RNA-binding motif
Homologous_superfamily	IPR012677	Nucleotide-binding alpha-beta plait domain superfamily
Homologous_superfamily	IPR035979	RNA-binding domain superfamily

Domain Details Per Protein

Protein	Length	Nucleotide-binding alpha-beta plait domain superfamily	RBM1CTR	RNA-binding domain superfamily	RNA-binding motif	RNA recognition motif domain	RNA recognition motif domain, eukaryote
UniProtKB:Q7ZWA3 InterPro	379
UniProtKB:A0A8M6Z2K5 InterPro	374
UniProtKB:A0A8M9QP18 InterPro	379
UniProtKB:A0A8M9QKH0 InterPro	277

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
aberrant processed transcript	rbmx-204 (1) Ensembl	Ensembl	1,145 nt	Select Tool
mRNA	rbmx-201 (1) Ensembl	Ensembl	882 nt	Select Tool
mRNA	rbmx-202 (1) Ensembl	Ensembl	1,560 nt	Select Tool
mRNA	rbmx-203 (1) Ensembl	Ensembl	888 nt	Select Tool
mRNA	rbmx-207 (1) Ensembl	Ensembl	386 nt	Select Tool
mRNA	rbmx-208 (1) Ensembl	Ensembl	1,456 nt	Select Tool ZFIN BLAST
ncRNA	rbmx-003 (1) Ensembl	Ensembl	1,094 nt	Select Tool
ncRNA	rbmx-005 (1) Ensembl	Ensembl	721 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations