Gene

arid1ab

ID

ZDB-GENE-030131-5725

Name

AT-rich interactive domain 1Ab

Symbol

arid1ab Nomenclature History

Previous Names

fb82h08
fi15b05
im:7160733
si:dkey-180c19.1
wu:fb82h08
wu:fi15b05

Type

protein_coding_gene

Location

Chr: 19 Mapping Details/Browsers

Description

Predicted to contribute to nucleosome binding activity. Predicted to be involved in ATP-dependent chromatin remodeling; positive regulation of transcription, DNA-templated; and regulation of transcription by RNA polymerase II. Predicted to localize to SWI/SNF complex; nBAF complex; and nucleoplasm. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome 2 and neuroblastoma. Orthologous to human ARID1A (AT-rich interaction domain 1A).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7160733 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With arid1ab Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
Coffin-Siris syndrome 2	Alliance	Coffin-Siris syndrome 2	614607

Associated With arid1ab Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001606	ARID DNA-binding domain
Domain	IPR033388	SWI/SNF-like complex subunit BAF250, C-terminal
Family	IPR021906	SWI/SNF-like complex subunit BAF250/Osa
Homologous_superfamily	IPR011989	Armadillo-like helical
Homologous_superfamily	IPR036431	ARID DNA-binding domain superfamily

Domain Details Per Protein

Protein	Length	ARID DNA-binding domain	ARID DNA-binding domain superfamily	Armadillo-like helical	SWI/SNF-like complex subunit BAF250, C-terminal	SWI/SNF-like complex subunit BAF250/Osa
UniProtKB:A0A8M9PSC1 InterPro	2261

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	arid1ab-202 (1) Ensembl	Ensembl	6,303 nt	Select Tool
mRNA	arid1ab-203 (1) Ensembl	Ensembl	10,429 nt	Select Tool ZFIN BLAST
ncRNA	arid1ab-002 (1) Ensembl	Ensembl	475 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations