Gene
tuba4l
- ID
- ZDB-GENE-030131-5588
- Name
- tubulin, alpha 4 like
- Symbol
- tuba4l Nomenclature History
- Previous Names
-
- fi05b01
- wu:fi05b01
- zgc:76934 (1)
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Predicted to act upstream of or within microtubule-based process. Predicted to be located in cytoskeleton. Predicted to be active in cytoplasm and microtubule. Human ortholog(s) of this gene implicated in autosomal dominant isolated macrothrombocytopenia 2. Orthologous to human TUBA3C (tubulin alpha 3c); TUBA8 (tubulin alpha 8); and TUBAL3 (tubulin alpha like 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017975 | Tubulin, conserved site |
| Domain | IPR003008 | Tubulin/FtsZ, GTPase domain |
| Domain | IPR018316 | Tubulin/FtsZ, 2-layer sandwich domain |
| Family | IPR000217 | Tubulin |
| Family | IPR002452 | Alpha tubulin |
| Homologous_superfamily | IPR008280 | Tubulin/FtsZ, C-terminal |
| Homologous_superfamily | IPR023123 | Tubulin, C-terminal |
| Homologous_superfamily | IPR036525 | Tubulin/FtsZ, GTPase domain superfamily |
| Homologous_superfamily | IPR037103 | Tubulin/FtsZ-like, C-terminal domain |
Domain Details Per Protein
| Protein | Additional Resources | Length | Alpha tubulin | Tubulin | Tubulin, conserved site | Tubulin, C-terminal | Tubulin/FtsZ, 2-layer sandwich domain | Tubulin/FtsZ, C-terminal | Tubulin/FtsZ, GTPase domain | Tubulin/FtsZ, GTPase domain superfamily | Tubulin/FtsZ-like, C-terminal domain |
|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q6TGS5 | InterPro | 449 | |||||||||
| UniProtKB:A0AB32U186 | InterPro | 456 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| aberrant processed transcript |
tuba4l-202
(1)
|
Ensembl | 772 nt | ||
| mRNA |
tuba4l-201
(1)
|
Ensembl | 1,516 nt | ||
| mRNA |
tuba4l-203
(1)
|
Ensembl | 3,449 nt |
Interactions and Pathways
No data available
Plasmids
No data available