Gene
kpna4
- ID
- ZDB-GENE-030131-5584
- Name
- karyopherin alpha 4 (importin alpha 3)
- Symbol
- kpna4 Nomenclature History
- Previous Names
-
- wu:fa56d07
- wu:fa66g10
- wu:fe14c04
- wu:fi04h11
- wu:fi19b05
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to enable nuclear import signal receptor activity and nuclear localization sequence binding activity. Predicted to be involved in NLS-bearing protein import into nucleus. Predicted to act upstream of or within protein import into nucleus. Predicted to be located in cytoplasm. Predicted to be active in nucleoplasm. Orthologous to human KPNA4 (karyopherin subunit alpha 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55488 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Ping et al., 2021
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR002652 | Importin-alpha, importin-beta-binding domain |
| Family | IPR024931 | Importin subunit alpha |
| Homologous_superfamily | IPR011989 | Armadillo-like helical |
| Homologous_superfamily | IPR016024 | Armadillo-type fold |
| Homologous_superfamily | IPR036975 | Importin-alpha, importin-beta-binding domain superfamily |
| Repeat | IPR000225 | Armadillo |
| Repeat | IPR032413 | Atypical Arm repeat |
Domain Details Per Protein
| Protein | Length | Armadillo | Armadillo-like helical | Armadillo-type fold | Atypical Arm repeat | Importin-alpha, importin-beta-binding domain | Importin-alpha, importin-beta-binding domain superfamily | Importin subunit alpha |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q7ZVY9
|
521 |
Interactions and Pathways
No data available
Plasmids
No data available