Gene
rgs14a
- ID
- ZDB-GENE-030131-5579
- Name
- regulator of G protein signaling 14a
- Symbol
- rgs14a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to have G-protein alpha-subunit binding activity; GTPase regulator activity; and microtubule binding activity. Involved in germ cell migration. Human ortholog(s) of this gene implicated in nephrolithiasis. Is expressed in blastomere; epidermis; neural crest; and primordial germ cell. Orthologous to human RGS10 (regulator of G protein signaling 10) and RGS14 (regulator of G protein signaling 14).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 11 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:66445 (1 image)
- IMAGE:7160274 (9 images)
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Hartwig et al., 2014
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR003109 | GoLoco motif |
| Domain | IPR003116 | Raf-like Ras-binding |
| Domain | IPR016137 | RGS domain |
| Domain | IPR046992 | Regulator of G-protein signaling 14, Ras-binding domain 1 |
| Domain | IPR046993 | Regulator of G protein signaling 14, Ras-binding domain 2 |
| Family | IPR046995 | Regulator of G-protein signaling 10/12/14-like |
| Homologous_superfamily | IPR024066 | RGS, subdomain 1/3 |
| Homologous_superfamily | IPR029071 | Ubiquitin-like domain superfamily |
| Homologous_superfamily | IPR036305 | RGS domain superfamily |
| Homologous_superfamily | IPR044926 | RGS, subdomain 2 |
Domain Details Per Protein
| Protein | Length | GoLoco motif | Raf-like Ras-binding | Regulator of G-protein signaling 10/12/14-like | Regulator of G-protein signaling 14, Ras-binding domain 1 | Regulator of G protein signaling 14, Ras-binding domain 2 | RGS domain | RGS domain superfamily | RGS, subdomain 1/3 | RGS, subdomain 2 | Ubiquitin-like domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M3B8C4
|
554 | ||||||||||
|
UniProtKB:Q7SXC7
|
532 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
rgs14a-201
(1)
|
Ensembl | 2,495 nt | ||
| mRNA |
rgs14a-202
(1)
|
Ensembl | 647 nt | ||
| mRNA |
rgs14a-204
(1)
|
Ensembl | 859 nt | ||
| ncRNA |
rgs14a-004
(1)
|
Ensembl | 240 nt |
Interactions and Pathways
No data available
Plasmids
No data available