ZFIN ID: ZDB-GENE-030131-5557
Gene Name: myotubularin related protein 6
Gene Symbol: mtmr6    Nomenclature History

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Previous Names: wu:fi04a11, zgc:55289

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 24 Mapping Details/Browsers
Description: Predicted to have phosphatidylinositol phosphate phosphatase activity and protein tyrosine phosphatase activity. Predicted to be involved in phosphatidylinositol dephosphorylation. Orthologous to human MTMR6 (myotubularin related protein 6).
Genome Resources: Alliance (1),  Gene:327346 (1),  Ensembl(GRCz11):ENSDARG00000016794 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:55289]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa6770 Point Mutation Unknown Premature Stop ENU
sa18593 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa24510 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH mtmr6 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH mtmr6 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process dephosphorylation (more)
    Molecular Function phosphatase activity (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR000387 Tyrosine specific protein phosphatases domain
    Domain IPR003595 Protein-tyrosine phosphatase, catalytic
    Domain IPR010569 Myotubularin-like phosphatase domain
    Homologous_superfamily IPR011993 PH-like domain superfamily
    Active_site IPR016130 Protein-tyrosine phosphatase, active site
    Homologous_superfamily IPR029021 Protein-tyrosine phosphatase-like
    Family IPR030564 Myotubularin family
    Family IPR030581 Myotubularin-related protein 6
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA mtmr6-201 (1)    Ensembl 2739
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM mtmr6 No data available
    MARKER RELATIONSHIPS
    mtmr6 Contained in: [BAC] DKEY-11P10 (1) (order this)
    mtmr6 Encodes: [EST] fi04a11
    [cDNA] MGC:55289 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_199791 (1) 2754 bp
    Genomic GenBank:CR383672 (1) 231583 bp Blast at MegaBLAST
    Polypeptide UniProtKB:F1QFI4 (1) 643 aa
    Sequence Information (all 11)
    ORTHOLOGY for mtmr6 ( Chr: 24 )
    CITATIONS (18)