ZFIN is now using GRCz12tu for Genomic Data
Gene
n4bp1
- ID
- ZDB-GENE-030131-5538
- Name
- nedd4 binding protein 1
- Symbol
- n4bp1 Nomenclature History
- Previous Names
-
- wu:fi03b05
- zgc:66437 (1)
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable RNA nuclease activity; mRNA binding activity; and ubiquitin binding activity. Predicted to be involved in several processes, including negative regulation of cytokine production; negative regulation of protein metabolic process; and negative regulation of viral genome replication. Predicted to act upstream of or within innate immune response. Predicted to be located in cytosol and nucleolus. Predicted to be active in PML body. Orthologous to human N4BP1 (NEDD4 binding protein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:66437 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR021869 | Ribonuclease Zc3h12a-like, NYN domain |
| Domain | IPR056578 | N4BP1, C-terminal UBA domain |
| Domain | IPR056629 | N4BP1, first type I KH-domain |
| Domain | IPR056630 | N4BP1, second type I KH-domain |
| Domain | IPR056631 | N4BP1, UBA-like domain |
| Family | IPR051101 | ZC3H12/N4BP1 Ribonuclease and Regulator |
| Homologous_superfamily | IPR036612 | K Homology domain, type 1 superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | K Homology domain, type 1 superfamily | N4BP1, C-terminal UBA domain | N4BP1, first type I KH-domain | N4BP1, second type I KH-domain | N4BP1, UBA-like domain | Ribonuclease Zc3h12a-like, NYN domain | ZC3H12/N4BP1 Ribonuclease and Regulator |
|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q1LVK9 | InterPro | 858 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers