Gene
ap1s2
- ID
- ZDB-GENE-030131-5448
- Name
- adaptor related protein complex 1 subunit sigma 2
- Symbol
- ap1s2 Nomenclature History
- Previous Names
-
- wu:fb94g06
- wu:fd19a08
- zgc:65824
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to be involved in vesicle-mediated transport. Predicted to act upstream of or within protein transport. Predicted to be located in membrane. Predicted to be part of membrane coat. Predicted to be active in intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability 5. Orthologous to human AP1S2 (adaptor related protein complex 1 subunit sigma 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:77925 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| syndromic X-linked intellectual disability 5 | Alliance | Pettigrew syndrome | 304340 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Adaptor protein complex, sigma subunit | AP-1 complex subunit sigma | AP complex, mu/sigma subunit | Clathrin adaptor complex, small chain | Longin-like domain superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:Q6P0R9
|
157 |
Interactions and Pathways
No data available
Plasmids
No data available