Gene
hyou1
- ID
- ZDB-GENE-030131-5344
- Name
- hypoxia up-regulated 1
- Symbol
- hyou1 Nomenclature History
- Previous Names
-
- id:ibd5056
- wu:fd14c05
- zgc:56019
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to have ATP binding activity. Predicted to be involved in cellular response to hypoxia and negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway. Predicted to localize to endoplasmic reticulum chaperone complex. Is expressed in several structures, including anterior axial hypoblast; digestive system; hatching gland; immature eye; and polster. Human ortholog(s) of this gene implicated in immunodeficiency 59. Orthologous to human HYOU1 (hypoxia up-regulated 1).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 12 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7141613 (3 images)
- IMAGE:6895638 (5 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
immunodeficiency 59 | Alliance | ?Immunodeficiency 59 and hypoglycemia | 233600 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Conserved_site | IPR018181 | Heat shock protein 70, conserved site |
Family | IPR013126 | Heat shock protein 70 family |
Family | IPR050451 | Heat Shock Protein 70 (HSP70) |
Homologous_superfamily | IPR029047 | Heat shock protein 70kD, peptide-binding domain superfamily |
Homologous_superfamily | IPR029048 | Heat shock protein 70kD, C-terminal domain superfamily |
Homologous_superfamily | IPR043129 | ATPase, nucleotide binding domain |
Domain Details Per Protein
Protein | Length | ATPase, nucleotide binding domain | Heat shock protein 70, conserved site | Heat shock protein 70 family | Heat Shock Protein 70 (HSP70) | Heat shock protein 70kD, C-terminal domain superfamily | Heat shock protein 70kD, peptide-binding domain superfamily |
---|---|---|---|---|---|---|---|
UniProtKB:Q7ZUW2
|
980 | ||||||
UniProtKB:B2GRZ4
|
980 |
Interactions and Pathways
No data available
Plasmids
No data available